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114. Damage to the capsule, vol. Thus, in spite of years of intensive study, many key areas remain only partially defined. 26 7. 0 B. 2s whereby the system behaves as if L and C were absent, and the pressure and R-scaled flow curves again become identical. In most cases the gain of function is related to conversion of the wild-type receptor that is dependent on agonist stimulation to a constitutively active recep- tor that is not dependent on activating ligand.

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